Plant Transcription Factor Database
Previous version: v3.0
Oryza sativa subsp. japonica
AP2 Family
Species TF ID Description
LOC_Os01g67410.1AP2 family protein
LOC_Os02g40070.1AP2 family protein
LOC_Os03g56050.1AP2 family protein
LOC_Os03g60430.1AP2 family protein
LOC_Os03g60430.2AP2 family protein
LOC_Os04g42570.1AP2 family protein
LOC_Os04g55560.2AP2 family protein
LOC_Os04g55560.3AP2 family protein
LOC_Os04g55970.2AP2 family protein
LOC_Os05g03040.1AP2 family protein
LOC_Os05g03040.2AP2 family protein
LOC_Os05g03040.3AP2 family protein
LOC_Os05g45954.1AP2 family protein
LOC_Os06g05340.1AP2 family protein
LOC_Os06g43220.1AP2 family protein
LOC_Os07g13170.1AP2 family protein
LOC_Os07g13170.2AP2 family protein
LOC_Os11g03540.1AP2 family protein
LOC_Os11g19060.1AP2 family protein
LOC_Os12g03290.1AP2 family protein
LOC_Os03g19900.1AP2 family protein
LOC_Os04g55970.1AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444

Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102